Background. Lichen Planus is a chronic mucocutaneous disease of immunological basis and unknown etiology. women with oral\r\nlichen planus may have concomitant manifestations in vulvovaginal areas. Objective. To determine the frequency and risk factors\r\nof genital involvement in a group of Iranian women affected by oral lichen planus. Methods. Thirty-six women with clinical and\r\nhistopathological diagnosis of oral lichen planus were evaluated for demographic, historical, and clinical parameters of the oral\r\ndisease. All the patients were referred for careful vulvovaginal examination, as well as histopathological assessment upon clinical\r\nindication. Results. Nineteen patients complained from genital symptoms but the number of women with the final diagnosis of\r\ngenital lichen planus (n = 2) was too small to show any correlation with the parameters evaluated. Conclusion. In spite of low\r\ngenital involvement possibly due to inadequate patient population, lack of follow-up visits, and contribution of genetic or ethnic\r\nfactors, for conservative patient care, women with the oral lichen planus in particular those having some relevant genital symptoms,\r\nshould preferably be referred for careful vulvovaginal examination.Multicenter cohort studies on women of different geographical\r\nregions or ethnicities who have genital lichen planus alone or in combination with other common sites are encouraged.
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